Hey,
I know I am a girl and all, but I am a backpack guide and can carry my fair share. The thing about a huge pack and being in the cities is it is hard to get on and off trains, buses, planes, and so forth.
I would say go for a 70 lt. , anything more will just hold you back. Especially if you are not doing a lot of walking and more relying on public transport. I used one that size for 3 months in Costa Rica and it did me just fine. Just big enough to hold it all, and small enough that it did not become a huge hassle.
Good luck!
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Don't take life to seriously, you will never get out alive. - Van Wilder
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